Wilms' tumor with right heart extension: Report of a post-chemotherapeutic fatality.
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Date
2012-07
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Abstract
Wilms' tumor (WT) has a strong propensity to invade the vasculature in the form of tumor-thrombus, into the renal veins, and inferior vena cava and even into the right atrium. This cavo-atrial propagation does not alter the prognosis and pre-operative chemotherapy produces shrinkage to the extent of even disappearance of caval or atrial extensions. We present a case of sudden death due to hemorrhagic expansion of the intra-atrial component of WT, immediately after commencement of chemotherapy, an uncommon incident.
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Keywords
Chemotherapy, children, heart, intracardiac metastases, right atrium, wilm′s tumor
Citation
Vaideeswar Pradeep, Chaudhari Jayashri P. Wilms' tumor with right heart extension: Report of a post-chemotherapeutic fatality. Indian Journal of Pathology & Microbiology. 2012 Jul-Sept 55(3): 381-383.