Hemophagocytic syndrome associated with Plasmodium falciparum infection.
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Date
2011-07
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Abstract
Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of an 11-month-old infant with fever, hepatosplenomegaly, pancytopenia, high serum ferritin, hypertriglyceridemia, and bone marrow hemophagocytosis, consistent with hemophagocytic syndrome. Gametocytes of plasmodium falciparum were identified on bone marrow aspiration. Rapid recovery was observed after treatment with antimalarials.
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Keywords
Hemophagocytic syndrome, Plasmodium falciparum, pancytopenia
Citation
Vinoth P N, Thomas K Abilash, Selvan S Muthamil, Suman D Febe Renjitha, Scott Julius Xavier. Hemophagocytic syndrome associated with Plasmodium falciparum infection. Indian Journal of Pathology & Microbiology. 2011 Jul-Sept 54(3): 594-596.