Pulmonary carcinosarcoma masquerading as a cryptic disseminated malignancy.
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Date
2009-10
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Abstract
Pulmonary carcinosarcoma is an aggressive rare malignant tumor comprising a mixture of carcinoma and sarcoma components containing differentiated mesenchymal elements, such as malignant cartilage, bone, and skeletal muscle. We report a case which presented with unusual clinical features and proved cryptic until death. At autopsy, it was a stage IV lung malignancy and histopathology revealed a carcinosarcoma comprising an adenocarcinoma and an osteosarcoma with metastasis to the heart, lymph nodes, and both adrenals. To our knowledge, this is the first case of this subtype with metastasis to the heart. The present case had an unusual clinical presentation and its elusive nature towards diagnosis despite dissemination is noteworthy and unique in the literature.
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Keywords
Pulmonary carcinosarcoma, thromboembolism, metastasis heart
Citation
Kaur Amulyajit, Falleiro J J J, Ghosh A K, Mani N S. Pulmonary carcinosarcoma masquerading as a cryptic disseminated malignancy. Indian Journal of Pathology & Microbiology. 2009 Oct-Dec; 52(4): 517-519.