Quality of life assessment of patients with chronic liver disease in eastern India using a Bengali translation chronic liver disease questionnaire.
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Date
2010-09
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Abstract
Aims The aim of this study was to translate and validate chronic liver disease questionnaire (CLDQ) into Bengali
using a standard protocol and use it to assess the impact
of socioeconomic factors, etiology, disease severity and
complications on the quality of life of patients.
Methods Formal translation of CLDQ to Bengali was done.
Cronbach’s alpha and test-retest was performed for reliability
analysis. Patients with clinically stable chronic liver disease
(CLD) without significant associated co-morbid states were
administered Bengali CLDQ in the Liver Clinic. The clinical,
biochemical and disease parameters were recorded for analysis.
Results Bengali CLDQ was administered to 100 patients
with CLD. Cronbach’s alpha of overall scores was 0.90 and
test-retest correlation coefficient of average CLDQ was
0.86 (P<0.001). Patients with history of decompensation
(96.51 vs. 109.61; P=0.039) and Child’s C status (92.24 vs.
105.71; P=0.028) had significantly lower CLDQ scores.
CLDQ scores showed a moderate inverse correlation with
Child’s status (r=−0.35) and a poor correlation with MELD
score (r=−0.09).
Conclusion Bengali translation of CLDQ was found to be
reliable. History of decompensation, Child’s C status was
associated with worse CLDQ scores. Child’s status may have
some role in predicting quality of life of patients with CLD. MELD score had poor predictability of quality of life.
Description
Keywords
Alcoholic liver disease, Chronic hepatitis B, Chronic hepatitis C, Quality of life, Questionnaire
Citation
Ray Irene, Dutta Deep, Basu Pallavi, De Binay K. Quality of life assessment of patients with chronic liver disease in eastern India using a Bengali translation chronic liver disease questionnaire. Indian Journal of Gastroenterology. 2010 Sept-Oct; 29(5): 187-195.