Selective histopathology in cholecystectomy for gallstone disease.
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Date
2010-01
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Abstract
Background Incidental gallbladder cancer is found in upto
1% of cholecystectomy specimens for gallstone disease. Currently,
in our institution, all gallbladder specimens are sent for
routine histopathology, to rule out incidental gallbladder carcinoma.
This study was aimed at assessing the need for routine
histopathology of gallbladder specimens after cholecystectomy
for gallstone disease.
Methods Hospital records of all patients undergoing cholecystectomy
for gallstone disease over a ten-year period, between
1998 and 2007, in a single surgical unit were reviewed.
Results A total of 1312 patients underwent cholecystectomy
for gallstone disease. Gallbladder carcinoma was detected in
13 patients. Macroscopic abnormalities of the gallbladder were
found in all the 13 patients. In patients with a macroscopically
normal gallbladder, there were no cases of gallbladder
carcinoma.
Conclusion Gallbladder carcinoma is associated with macroscopic
abnormalities in all cases. Therefore histopathology
should be restricted to only those specimens which reveal a macroscopic abnormality. This would identify all cases of incidental gallbladder carcinoma, at the same time decreasing cost and pathological work load.
Description
Keywords
Incidental gallbladder cancer, routine surgical pathology
Citation
Mittal Rohin, Jesudason Mark Ranjan, Nayak Sukria. Selective histopathology in cholecystectomy for gallstone disease. Indian Journal of Gastroenterology. 2010 Jan-Feb; 29(1): 32-36.