Generalized eruptive histiocytosis mimicking leprosy.
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Date
2011-07
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Abstract
Generalized eruptive histiocytosis (GEH) is a rare cutaneous histiocytosis that mainly affects adults and presents with multiple symmetric papules on face, trunk, and proximal extremities. GEH is included in type IIa (histiocytes involving cells of dermal dendrocyte lineage) of histiocytic disorders. Clinical and pathological correlations are required for differentiating GEH from other histiocytic disorders and from lepromatous leprosy which clinically mimic GEH and is prevalent in India. We report a case of a middle-aged woman who presented with generalized asymptomatic papules and nodules and was treated for leprosy but was finally diagnosed to have GEH after clinical, histopathological, and immunohistochemical correlation. Furthermore, the newer lesions also showed features of progressive nodular histiocytosis.
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Keywords
Generalized eruptive histiocytosis, immunohistochemistry, leprosy, progressive nodular histiocytosis
Citation
Kumar B C Sharath, Nandini A S, Niveditha S R, Gopal M G, Reeti. Generalized eruptive histiocytosis mimicking leprosy. Indian Journal of Dermatology, Venereology and Leprology. 2011 Jul-Aug; 77(4): 498-502.