Subcutaneous phaeohyphomycosis caused by cladophialophora boppii.
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Date
2010-11
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Abstract
Subcutaneous phaeohyphomycosis is an infection of the skin and subcutaneous tissue, caused by dematiaceous fungi. An adult male presented with a history of multiple reddish nodules over the face and hands. Histopathological examination of the skin biopsies showed a dense granulomatous infiltrate of macrophages, containing intracytoplasmic basophilic bodies throughout the dermis. Gomori methenamine-silver stained sections revealed yeast cells within macrophages. Multiple cultures on Sabouraud's dextrose agar grew Cladophialophora boppii. The patient was treated with oral itraconazole for a year and the response monitored with dermal ultrasound. This is the first case report of subcutaneous phaeohyphomycosis caused by Cl. boppii in India.
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Keywords
Phaeohyphomycosis, dematiaceous fungi, Cladophialophora boppii, ultrasound biomicroscopy, itraconazole
Citation
Pereira Rickson R, Nayak Chitra S, Deshpande Sunita D, Bhatt Kalpana D, Khatu Swapna S, Dhurat Rachita S. Subcutaneous phaeohyphomycosis caused by cladophialophora boppii. Indian Journal of Dermatology, Venereology and Leprology. 2010 Nov-Dec; 76(6): 695-698.