Bioavailability of elixir theophylline (siriraj formula) in Thai asthmatic children.
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Date
1989-03
Authors
Habanananda, Suprida
Tuchinda, Montri
Koysooko, Renu
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Abstract
The bioavailability of Elixir Theophylline (Siriraj Hospital Formula) and Table Aminophylline (The Government Pharmaceutical Association) was compared with Elixir Quibron in Thai asthmatic children. The mean rate of absorption and the extent of drug absorption were not significantly different for local made drugs, compared with that of an imported one. With regards to the mean maximum serum levels (Cmax) and time to maximum serum level (Tmax) values, there were also no significant differences between two local preparations and an innovative one. Thus, the results suggest that the local made theophylline drugs possess the same efficacy as the imported drug.
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Keywords
Elixir theophylline, Asthmatic children
Citation
Habanananda Suprida, Tuchinda Montri, Koysooko Renu. Bioavailability of elixir theophylline (siriraj formula) in Thai asthmatic children. Siriraj Medical Journal, 1989 Mar; 41(3): 155-158.