Reference values for serum fructosamine of selected healthy Thais.
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Date
1992-12
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Abstract
The level of fructosamine was determined in the serum of 278 individuals ranging in age from 20 to 80 years who passed a physical check-up. The 130 males and 148 females had mean ages + standard deviation of 44.0+15.0 and 40.3+12.0 years, respectively. Serum fructosamine concentration was assayed using nitroblue tetrazoleum (NBT) reduction in alkaline medium. The reference values of serum fructosamine were 226 µmol/L to 296 µmol/L (Mean = 260.7, SD = 17.6 µmol/L). The serum fructosamine is unaffected by sex. Effect of food intake on fruc tosamine level has been carried out on a group of healthy subjects (n = 36). The means and SDs of serum fructosamine at eight-hour fasting, two-hour post-prandial and non-fasting specimens were studied and values of 269.4+17.9, 269.3+14.8 and 268.6+15.3 µmol/L respectively, were obtained. Results reveal that food intake has virtually no effect on fructosamine values (Analysis of variance p>0.05).
Parallel assays of 46-paired sera was Y = 17.5 + 0.95 X, whereas X and Y were serum and plasma fructosamine levels, respectively. Values of plasma fructosamine were statistical significantly difference from those of serum (p<0.001). A small discrepancy of 1.9 percent was observed. Thus, whenever plasma is used as sample for fructosamine test, a slightly higher value of fructosamine would be obtained.
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Keywords
Reference values, Serum fructosamine, Healthy thais
Citation
Kanluan Taweesuk, Intaramanee Srisanit, Tantrarongroj Soontharee, Tangvarasittchai Orathai, Suwanton Lerson, Tangvarasittichai Surapon, Tansakul Sirirat. Reference values for serum fructosamine of selected healthy Thais. Siriraj Medical Journal, 1992 Dec; 44(12): 975-981.