Elevated serum transcobalamin II levels in patients with prolonged fever.
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Date
1995-07
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Abstract
Serum transcobalamin II levels were determined in 70 patients with prolonged fever. Twelve patients were found to have elevated serum TCII levels, i.e., 8 patients with salmonellosis, 3 patients with scrub typhus and 1 patient with pyrexia of unknown origin. There were no relationships between serum TCII levels and white blood cells, lymphocytes or monocytes. The possible mechanism producing increased serum TCIII levels in patients with salmonellosis and scrub typhus is the increased synthesis and release of TCII by the proliferative mononuclear phagocytic cells of the reticuloendothlial tissues such as spleen, liver, bone marrow and lymph nodes. This study gives the additional data that elevated serum TCII may occur not only in inflammatory disorders, autoimmune diseases, lymphoproliferative disorders, malignant histiocytosis and neoplasms, but also in infection with salmonellosis and scrub typhus.
Description
Keywords
Serum transcobalamin II, Prolonged fever
Citation
Areekul Suvit, Churdchu Korbkit, Paksanond Suporn, Thanomsak Wanyarat, Wilairatana Polrat. Elevated serum transcobalamin II levels in patients with prolonged fever. Siriraj Medical Journal, 1995 Jul; 47(7): 628-632.