Neuroleptic malignant syndrome in a diabetic patient with eye complication and acute psychosis.
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Date
1999-06
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Abstract
Neuroleptic malignant syndrome is a life-threatenting complica-tion of antipsychotic treatment. The prevalence is estimated to be 0.02 to 2.4 percent of patients exposed to dopamine receptor antagonists. Mortality rates are reported to be 10-20 percent. The important clinical signs and symptoms are severe muscle rigidity and fever. Other features are changes in level of consciousness ranging from confusion to coma, autonomic instability and laboratory evidence of muscle injury (eg, elevated CPK). We report a diabetic patient with eye complications and acute psychosis, developing neuroleptic malignant syndrome four days after receiving haloperidol 15 mg/day. The patient recovered well within 5 days after discontinuation of haloperidol and symptomatic treatment and had undergone an eye operation which yielded good result.
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Keywords
Neuroleptic malignant syndrome, Diabetic patient, Eye complication, Acute psychosis
Citation
Kooptiwoot Sirirat, Vuthiganond Sangchandra. Neuroleptic malignant syndrome in a diabetic patient with eye complication and acute psychosis. Siriraj Medical Journal, 1999 Jun; 51(6): 367-372.