Prevalence of HIV among blood donors in a tertiary care centre of north India.
Loading...
Date
2011-12
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background & objectives: India has the second highest HIV population in the world with about 2.5-3.0
million cases. HIV-2 cases among general and blood donor population have also been reported mostly
from west and south India. This single centre study was carried out to observe the HIV-1 and HIV-2
prevalence among blood donors from north India.
Methods: A total of 2,04,677 people were screened for the presence of HIV infection over the 11 year
period (1999 to 2009). Till 2004, a third generation ELISA kit was used. From 2005 till January 2009 all
tests were done using the fourth generation ELISA kit which detected the presence of HIV-1 P24 antigen
and anti-HIV antibodies. From February 2009 onwards, the kits used were Genscreen ULTRA HIV Ag-
Ab Assay.
Results: A total of 506 (0.247%) donors were found to be repeat reactive for HIV. Of these, 486 (96%)
donors tested using the Western blot were found positive for HIV-1 infection. Twenty (4%) donors
showed a negative Western blot result, none of the donors were found reactive for HIV-2 infection.
Interpretation & conclusions: The prevalence of HIV was 0.249 per cent among blood donors of north
India. No HIV-2 case was found among the studied blood donor population indicating that it is not a threat currently.
Description
Keywords
Donor screening, HIV-1, HIV-2, north India, prevalence
Citation
Makroo R N, Chowdhry Mohit, Bhatia Aakanksha, Arora Bhavna, Rosamma N L. Prevalence of HIV among blood donors in a tertiary care centre of north India. Indian Journal of Medical Research. 2011 Dec; 134(6): 950-953.