Clinical study of morus alba linn. on glycemic control and blood lipids in patients with type 2 diabetes: A preliminary study.
Loading...
Date
2006-10
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Effects of Morus alba-leaf extracts on glycemic control and blood lipids were carried out in 27 patients with newly diagnosed type 2 diabetes. Water extracts of Morus alba leaves at a dosage of 700 mg were given to the patients thrice daily for 8 weeks. The patients did not receive any concomitant medications for diabetes or hyperlipidemia. The mean fasting plasma glucose levels at baseline, week 2, week 4, week 6 and week 8 were 155.1, 179, 173.6, 183.9 and 185.8 mg/dl, respectively (p=0.04). The mean glycosylated hemoglobin levels at baseline and week 8 were 7.6% and 8.4%, respectively (p=0.002). The mean blood total cholesterol levels at baseline, week 2, week 4, week 6 and week 8 were 229.6, 211.2, 210.2, 204.5 and 199.4 mg/dl, respectively (p<0.001). The mean blood triglyceride levels at baseline, week 2, week 4, week 6 and week 8 were 235.4, 191.3, 174.5, 183.5 and 168.2 mg/dl, respectively (p=0.001). No patients experienced side effects of the treatment. Laboratory results on CBC, urine, blood electrolytes, renal function and liver function at baseline, week 2, week 4, week 6 and week 8 were not significantly different. Morus alba-leaf extracts have no hypoglycemic effect but they exert lipid lowering effects.
Description
Keywords
Hyperglycemia, hyperlipidemia, Morus alba, type 2 diabetes
Citation
Sinsatienporn Somsak, Boonrod Ubon, Chavalittumrong Pranee, Bunjob Malee, Anulukanapakorn Kalaya, Luanratana Omboon, Thongdaeng Phinai Hong, Thamlikitkul Visanu. Clinical study of morus alba linn. on glycemic control and blood lipids in patients with type 2 diabetes: A preliminary study. Siriraj Medical Journal, 2006 Oct; 58(10): 1039-1041.