Nasal provocation test: how to maximize its clinical use.
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Date
2010-12
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Abstract
In order to diagnose allergic rhinitis (AR), skin prick tests and serum specific IgE level are the most common used methods. But there are some conditions which the results of both methods do not correlate with the clinical presentation of AR. Nasal provocation test is the method of detecting local IgE at the shock organ. There are some variations of NPT in terms of dosage, allergen administration, evaluation and scoring system. This article summarized the usefulness of NPT, its indication and contraindication, dosage and instillation techniques for allergens and evaluation of outcome in the hope that if we can standardize the procedure and make it easier to perform, NPT will be applied more in clinical practice. In addition normal values among Asian ethnics are presented for appropriate interpretation of the test
Description
Keywords
Allergic rhinitis, Diagnosis, Skin prick test, Nasal provocation test, Peak nasal inspiratory flow, Acoustic rhinometry, Rhinomanometry
Citation
Tantilipikorn Pongsakorn, Vichyanond Pakit, Lacroix Jean Silvain. Nasal provocation test: how to maximize its clinical use. Asian Pacific Journal of Allergy and Immunology, 2010 Dec; 28(4): 225-231.