An Indian perspective on primary angle closure and glaucoma.
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Date
2011-01
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Abstract
Aim:
To provide a synopsis of primary angle closure disease in India, and Indian studies on the same.
Results:
Primary angle closure glaucoma forms almost half of all adult primary glaucomas seen in a hospital setting in India. Anatomically, corneal diameters and anterior chamber depths were least in acute and chronic PACG eyes as compared to subacute eyes and controls. Besides relative pupillary block, a Valsalva maneuver during activities of daily living may be responsible for intermittent angle closure and raised IOP in predisposed eyes. Iridotomy alone, controlled the intraocular pressure in 66.7% of subacute eyes and 12.9% of the acute. Medical therapy was additionally required for 35.5% of the acute eyes, 12.1% of the subacute and 30.0% of the chronic cases. There was a greater mean and peak IOP reduction, achieved with 0.005% latanoprost once daily, 8.2 ± 2.0 mm Hg, compared with 0.5% timolol twice daily, 6.1 ± 1.7 mm Hg2. A progression of PACS to PAC was seen in 22%, PAC to PAC OHT in 38.7% and PAC OHT to PACG in 30.7% over 5 years.
Conclusions:
Primary angle closure disease is common in India, and can be managed well with iridotomy, followed by an appropriate control of IOP.
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Keywords
Primary angle closure, glaucoma, India, primary angle closure glaucoma, primary angle closure disease
Citation
Sihota Ramanjit. An Indian perspective on primary angle closure and glaucoma. Indian Journal of Ophthalmology. 2011 Jan; 59 (Suppl1): 76-81.