Molecular mechanism of acquisition of the cholera toxin genes.
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Date
2011-02
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Abstract
One of the major pathogenic determinants of Vibrio cholerae, the cholera toxin, is encoded in the genome of a filamentous phage, CTX. CTX makes use of the chromosome dimer resolution system of V. cholerae to integrate its single stranded genome into one, the other, or both V. cholerae chromosomes. Here, we review current knowledge about this smart integration process.
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Keywords
dif, site-specific recombination, XerC, XerD
Citation
Das Bhabatosh, Bischerour Julien, Barre François-Xavier. Molecular mechanism of acquisition of the cholera toxin genes. Indian Journal of Medical Research. 2011 Feb; 133(2): 195-200.