Compative Erythropietin Levelsinurine of the Anemic and Malnourished Patients

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Date
2010-05-15
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Faculty of Medicine, Khon Kaen University
Abstract
The\  24 \– hour\  urinary\  excretion\  of\  erythropoietin\  was\  biologically\  assayed\  in\  the\  33\  anemic\  patients\  and\  the\  8\  patients\  with\  protein \– energy\  malnutrition\  from\  Chiang\  Mai\  Hospital,\  Chiang\  Mai\  university,\  Thailand. The\  erythropoietic\  activity\  in\  the\  patients\’\  urine\  was\  measured\  by\  radiobiological\  technique\  in\  starved\  rats,\  comparing\  with\  that\  of\  the\  18 healthy\  subjects\  living\  in\  the\  same\  area.\  This\  investigation\  indicates\  that\ \  the\  urinary\  erythropoietin\  level\  in\  patients\  with all\  types\  of\  animas\  is\  approximately\  62\  per\  cent\  higher\  than\  in\  the\  malnourished\  patients.\  The\  average\  urinary\  erythropoietic\  activity\  of\  anemic\  patients\  is\  297 .11 \  46.95\  Co\  Units\  per\  24 \– hour\  Urine,\  While\  that\  of\  the\  patients\  with\  protein \– energy\  malnutrition\  is\  only\  187 .66\  \  16.15\  Co\  Units\  per\  24 \– hour\  Urine.\  In\  the\  case\  of\  anemic\  patients,\  the\  urinary\  erythropoietin level\  in\  patients,\  the\ \  urinary\  erythropietin\  level\  in\  aplastic\  anemia\  is\  the\  highest\  among\  the\  group,\  in\  which\  the\  average\  activity\  is\  equal\  to\  725.94  88.31\  Co\  Units\  per\  24 hour\  Urine.\ 
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Citation
Srinagarind Medical Journal (SMJ); Vo. 8 No. 2 April - June 1993; 91-96