MICROBIAL KERATITIS LEADING TO ADMISSION AT MAHARAJ NAKORN CHIANG MAI HOSPITAL
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2010-01-01
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Chiang Mai Medical Journal
Abstract
Objective Methods Results Pseudomonas (39%) was the most common bacteria isolated. The principalfungal species isolated werefusarium (14%) and aspergillus (7%). Sixty nine eyes requiredsurgical interventions and 16 of these eventually underwent either evisceration or enucleation.One hundred and twenty seven eyes (60%) improved in unaided visual acuity of one or morelines after treatment.Conclusion Pseudomonas is the predominant causative organism in bacterial keratitis,and filamentous fungi are the principal causes of fungal keratitis. A bacterial: fungal ratio inthis setting is 3 : 2, which appears to be expected in the tropic.Chiang Mai Med Bull2004;43(3):93-103.Antecedent ocular trauma is the main risk factor for microbial keratitis innorthern Thailand.Two hundred and fourteen eyes of 213 consecutive patients (mean age 44.4 (SD36)years) were studied. The common risk factors in this study were trauma including foreignbodies (44%), preexisting ocular diseases (14%), contact lens wear (11%), and undeterminedcause (18%). Most of the patients (74%) had prior treatment from ophthalmologists, generalpractitioners and drug stores. Corneal scraping was performed in 190 eyes and 30% hadpositive culture results. Sixty percent of the offending organisms were bacteria and 40%were fungi.New cases of microbial keratitis were retrospectively reviewed over a period of 36months. Clinical features (demographics, risk factors, visual acuity), microbiologic studiesand clinical outcome were analyzed.To report the risk factors, microbiologic profile, therapeutic and visual results inpatients with microbial keratitis in the tertiary eye care center setting in northern Thailand.
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Chiang Mai Medical Journal; Vol.43 No.3 September 2004 (pages 93 - 127); 93 - 103