Comparative study between the invasive and non-invasive test for gastric acid secretion
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2001-12-01
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To compare the invasive and non-invasive tests for gastric acid secretion, 30 appearently healthy Myanmar male volunteers (25-45 years) were studied. After overnight fasting, they ingested 150 mg of Mg++ metal suspended in 3 mlof glucose and 100 ml of 7
ethanol on the first day and alcohol without Mg++ onthe second day. Basal gastric juice (by Ryle's tube), urine and breath H2 were collected. Another 11 samples of gastric juice and breath H2 were collected aftermeal for 180 minutes at 15 minute intervals. Hourly urine collection was also done for three hours. Acid contents of gastric juice aand urine were determined byconventional titraton method. Breath H2 was analyzed by microanalyzer (Quintron,Model 12 microlyzer). Correlation coefficients: between maximal acid output (15-60 minutes) and 2nd hour urine acid output-0.50(p<0.05); peak acid output (15-60minutes),0.44(p<0.05); and maximal acid output and breath hydrogen test (75-90 minutes), 0.40 (p<0.05). Thus non-invasive tests (Oral Magnesium Breath Hydrogen Test and urine acid output determination) may also be used as alternative tests in studying the gastric acid secretion.
ethanol on the first day and alcohol without Mg++ onthe second day. Basal gastric juice (by Ryle's tube), urine and breath H2 were collected. Another 11 samples of gastric juice and breath H2 were collected aftermeal for 180 minutes at 15 minute intervals. Hourly urine collection was also done for three hours. Acid contents of gastric juice aand urine were determined byconventional titraton method. Breath H2 was analyzed by microanalyzer (Quintron,Model 12 microlyzer). Correlation coefficients: between maximal acid output (15-60 minutes) and 2nd hour urine acid output-0.50(p<0.05); peak acid output (15-60minutes),0.44(p<0.05); and maximal acid output and breath hydrogen test (75-90 minutes), 0.40 (p<0.05). Thus non-invasive tests (Oral Magnesium Breath Hydrogen Test and urine acid output determination) may also be used as alternative tests in studying the gastric acid secretion.
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Mya Mya Thwin, Htay Htay, Khin Myo Chit, Lay Thet Htar, Myint Aye Mu. Comparative study between the invasive and non-invasive test for gastric acid secretion. Myanmar Medical Journal. 2001; 45(3-4): 98-101