A rare cause of steatohepatitis.

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2004-10-26
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We present a rare case of steatohepatitis due to neutral lipid storage disorder in a 1.5-year-old male presenting with intermittent fever, hepatomegaly and dark-coloured urine. On examination, there was ichthyosis involving both the limbs. Liver biopsy showed steatohepatitis. The peripheral blood smear revealed fat vacuoles in the cytoplasm of leucocytes, characteristic of the Dorfman-Chanarin syndrome. Awareness of this condition helps in prompt diagnosis and avoids unnecessary further investigations.
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Amarapurkar AD, Kher A, Agrawal R, Meenakshi B, Kandalkar BM, Deshpande JR. A rare cause of steatohepatitis. Tropical Gastroenterology. 2004 Oct-Dec; 25(4): 176-7