Cloning, chromosome localization and features of a novel human gene, MATH2.
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2002-04-03
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Abstract
We report cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2. Results of Northern blot analysis revealed two transcripts of the MATH2 gene of 1.7 kb and 2.4 kb in human brain. We localized MATH2 to chromosome 7 at 7p14-15 by matching with the Human Genome Sequence Database. Human MATH2 and mouse Math2 may have the same functions in the nervous system.
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Guo L, Jiang M, Ma Y, Cheng H, Ni X, Jin Y, Xie Y, Mao Y. Cloning, chromosome localization and features of a novel human gene, MATH2. Journal of Genetics. 2002 Apr; 81(1): 13-7