Local anaesthetic activity of some sec-amino-N-(aryl-aralkyl)-ethyl acetamides.

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Date
1978-07-01
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Abstract
Six basic amides were screened for local anaesthetic activity and compared with procaine and lignocaine. Amongst the basic amides screened, piperidino-N-(alpha-4-ethoxy phenyl- beta-phenyl) ethyl and Diethylamino-N (alpha-4-ethoxy- beta-phenyl) ethyl acetamide were found to be more effective as compared to lignocaine. They were found to be non-irritant, and non-toxic even in high doses.
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Gandhi TP, Modh PR, Shah GF, Patel VC. Local anaesthetic activity of some sec-amino-N-(aryl-aralkyl)-ethyl acetamides. Indian Journal of Physiology and Pharmacology. 1978 Jul-Sep; 22(3): 317-20
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https://imsear.searo.who.int/handle/123456789/108636
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Indian Journal of Physiology and Pharmacology