Effect of cold challenge on alveolar capillary blood volume in normal individuals.
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1990-10-01
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Abstract
The effect of immersion of both the hands and the feet in water at 10 degrees C on lung transfer factor for carbon monoxide (Tlco) and on pulmonary capillary blood volume (Vc) was investigated in 20 normal young adult males immediately, 60 min and 120 min after the end of the cold challenge. Vc was significantly reduced immediately and the reduction was aggravated at 60 min. Tlco was significantly reduced only at 60 min. All the values returned to baseline at 120 min. It is concluded that the cold-induced changes in Tlco and Vc are physiological responses and not unique to patients with Raynaud's phenomenon as suggested by some workers.
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Mishra N, Marya RK, Mahajan KK. Effect of cold challenge on alveolar capillary blood volume in normal individuals. Indian Journal of Physiology and Pharmacology. 1990 Oct; 34(4): 255-8