Effect of antihypertensive drugs on ethanol induced gastric lesions: is there a correlation with mucosal blood flow?

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1993-01-01
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Abstract
We studied the effect of five antihypertensive drugs on ethanol-induced gastric haemorrhagic lesions in rats. While hydralazine aggravates these lesions, nifedipine and propranolol have a protective action. On the other hand, enalapril and prazosin have no effect. Thus the effects of antihypertensive drugs on ethanol-induced lesions do not always correlate with their reported actions on gastric mucosal blood flow.
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Rataboli PV, Diniz D'Souza RS, Dhume VG. Effect of antihypertensive drugs on ethanol induced gastric lesions: is there a correlation with mucosal blood flow? Indian Journal of Physiology and Pharmacology. 1993 Jan; 37(1): 88-90
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https://imsear.searo.who.int/handle/123456789/108316
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Indian Journal of Physiology and Pharmacology