Anti-inflammatory and analgesic properties of four amino-acids.

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Date
1984-10-01
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Abstract
Orally administered L-isoleucine, DL-isoleucine and L-leucine exhibited anti-inflammatory activity in many test models of inflammation except formaldehyde-induced inflammation. L-beta-phenylalanine inhibited carrageenan-induced oedema only. L-isoleucine also exhibited prolonged analgesic effect while DL-isoleucine had a short lasting effect. The amino-acids produced no gastric ulceration or overt acute toxicity in doses which effectively suppress inflammation. Anti-inflammatory activity seems to be related with interference with the action and/or synthesis of prostaglandins and deserves further intensive study.
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Saxena RN, Pendse VK, Khanna NK. Anti-inflammatory and analgesic properties of four amino-acids. Indian Journal of Physiology and Pharmacology. 1984 Oct-Dec; 28(4): 299-305
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https://imsear.searo.who.int/handle/123456789/106657
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Indian Journal of Physiology and Pharmacology