The interaction of barbiturates and analeptics.

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1977-01-01
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Abstract
The interaction of pentobarbitone sodium with three analeptics viz. micoren, pentylenetetrazol and methedrine was studied in mice. Micoren prolonged pentobarbitone sleeping time. pentylenetetrazol shortened the sleeping time. Methedrine also shortened the sleeping time, but clonic convulsions of mild to severe intensity were noticed 45-60 minutes after the drug injection.
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Pundlik PG, Kaur S, Gupta SK. The interaction of barbiturates and analeptics. Indian Journal of Physiology and Pharmacology. 1977 Jan-Mar; 21(1): 75-7