Browsing by Author "Sultana, Nasrin"
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Item Conception of tuberculosis and evidence from slum area.(2015-10) Sultana, Nasrin; Tania, FatemaBackground: Tuberculosis (TB) remains as an important public health problem in Bangladesh. TB is an infectious bacterial disease caused by Mycobacterium tuberculosis, which most commonly affects the lungs. The common symptoms of tuberculosis include cough for a prolonged duration that is more than three weeks, unexplained or intended weight loss, fatigue, general feeling of tiredness, fever, sweating at night, chills and loss of appetite. The patients of Tuberculosis hide their disease from family, relatives, and community due to the presence of misconception. Methods: This cross-sectional study was done with 103 respondents .The objectives of this study were to assess knowledge of TB patients about their disease, and to identify their misconceptions associated with TB. The study was conducted to identify the conception regarding tuberculosis among the slum dweller in Shyamoli and Mohammmadpur area, in Dhaka city. Data were collected by face to face interview using semi-structured questionnaire. Results: Out of 103 respondents, among them 48.5% were in 15-25 years age group with mean 26.15; (SD = ± 5.34). More than two fifth (53.4%) respondents were male and 46.6t were female and 53.41% were educated up to primary level, 71.84% were married, 88% were Muslims, 26.21% respondents were Garment worker, 60.0% were lived in a nuclear family. Majority respondents (86.41%) live in tin shade house. Among the respondents 53.4% heard about TB disease and the main source of information was mass media(TV, Radio).Majority(70.87%) of respondents knew that Cough for more than 2 weeks is the Common Symptom of TB. Conclusions: Study findings shows that there is lots of misconception about tuberculosis but various TB control program are running in Bangladesh by Gob and different NGOs which can be help the people of our country to overcome the problems.Item In vitro interaction of Amoxicillin with Calcium Chloride (Fused) at pH 2.4 and pH 7.4.(2015-03) Sultana, Nasrin; Nath, Aninda Kumar; Islam, Md. Mohaiminul; Das, JoysreeThis study was aimed to evaluate the in vitro complexation nature and strength of complex which may be formed due to interaction between Amoxicillin and Calcium chloride (CaCl2). The interaction of Amoxicillin and Calcium chloride (fused) has been studied in aqueous systems at a fixed temperature (37 ± 0.5) °C and under different pH (pH 2.4 and pH 7.4) by using some physical methods as spectral observation, Job’s method of continuous variation, Ardon’s method. From spectrophotometric study, Amoxicillin gives a sharp peak at 272 nm when Calcium chloride mixed with Amoxicillin in 1:1 ratio the intensity of the peak of Amoxicillin change remarkably due to interaction. The jobs plot was obtained by plotting absorbance difference against the mole fraction of the each drug at pH 2.4 and pH 7.4. Amoxicillin forms strong 1:1 complex with Calcium chloride and reverse V Shaped curves indicate the formation of 1:1 complexes of Amoxicillin with Calcium chloride. These may indicate strong kinetics of complexation between Amoxicillin with Calcium chloride. The value of stability constant for the complexation of Amoxicillin with calcium chloride at pH 2.4 and pH 7.4 were obtained from the spectral data using Ardon’s plot. The value of stability constant for the drug-metal system at pH 2.4 and pH 7.4 are 5.54 and 6.67 respectively. At pH 2.4 it is found that Amoxicillin form relatively stable complex with Calcium chloride (stability constant 6.67) is high in comparison to pH 7.4. It can therefore be concluded that a careful consideration is needed during concurrent administration of Amoxicillin with Calcium chloride.Item Raised Vaginal Fluid Fibronectin Level Indicates Premature Rupture of Membrane.(2012-07) Rahman, Shamima; Jahan, Samsad; Habib, Samira Humaira; Sultana, Nasrin; Sultana, Mst Nigar; Paul, Debashish; Bhowmik, Amrita; Begum, KhodejaBackground: Premature rupture of membrane (PROM) is one of the common complications of pregnancy that has major impact on fetal and neonatal outcome. It is the commonest clinical event where a normal pregnancy becomes suddenly a high-risk one for mother and fetus or neonate. Objective: The study was undertaken to investigate whether raised fibronectin level in vaginal fluid may indicate premature rupture of membrane. Materials and Methods: This cross sectional study was conducted in the department of Obstetrics and Gynecology in Sir Salimullah Medical College & Mitford Hospital, Dhaka during the period of January 2006 to December 2007. A total of 114 pregnant women with gestational age 28th week up to 40th week were included. Sixty were PROM (Group I) and 54 were non-PROM (Group II) subjects. Fibronectin in vaginal fluid was measured by an immunochemical reaction by nephelometer. Statistical analysis was done by SPSS version 10.0. Results: The PROM patients had significantly higher concentration of fibronectin (225.77 ± 115.18 ng/mL) compared to that in non-PROM subjects (8.04 ± 16.17 ng/mL) (p < 0.001). Conclusion: It can be concluded that in cases of unequivocal rupture or intactness of the membranes, the result of the fibronectin test corresponds well with the clinical situation. So fibronectin is a sensitive test for detection of amniotic fluid in the vagina.