Browsing by Author "Mishra, D"
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Item Amebic liver abscess in an infant.(1969-12-01) Mishra, D; Mohanta, K DItem Awareness about taeniasis and neurocysticercosis among municipal schoolteachers in Delhi.(2007-12-14) Mishra, D; Kalra, V; Aggarwal, KTaenia solium is the commonest parasitic infection of CNS and an important cause of new-onset seizures and epilepsy in children and adults. Human activities impact on almost every one of the stages of the lifecycle of the worm as man is responsible for dispersion of the parasite's egg through outdoor defecation and indiscriminate disposal of feces. Health education to cause behavioral changes in these practices can therefore be an effective intervention strategy. We conducted a study to assess KAP regarding taeniasis and neurocysticercosis among municipal school teachers in Delhi. The findings are presented in this communication. The study revealed that, general information related to personal food hygiene was known to majority of the teachers but core information in the context of taeniasis/cysticercosis and seizure prevention was lacking.Item Burkholderia cepacia causing liver and splenic abscess: Two case reports(Wolters Kluwer - Medknow, 2023-03) Nittala, R; Behera, MK; Panigrahy, R; Narayan, J; Mishra, D; Singh, A; Pati, GK; Patil, S; Sahu, MK.Burkholderia cepacia infections are common among immunocompromised patients but multiple reports have shown that it can affect immunocompetent patients also. We are reporting two patients with multiple liver and splenic abscesses caused by Burkholderia cepacia. First case is a 54-year-old diabetic male presenting with fever, abdominal pain, bilateral lower limb weakness, and incontinence of urine. Second case is a 41-year-old male presenting with fever and confusion. Both had liver and splenic abscesses. Pus aspirated from the abscesses grew Burkholderia cepacia. Both responded to cotrimoxazole. Our case report emphasizes growing incidence of Burkholderia cepacia in immunocompetent patients.Item Comparison of optical coherence tomography angiography and fundus fluorescein angiography features of retinal capillary hemangioblastoma(All India Ophthalmological Society, 2018-06) Sagar, P; Rajesh, R; Shanmugam, M; Konana, VK; Mishra, DThe aim of this study is to compare the optical coherence tomography angiography (OCTA) and fundus fluorescein angiography (FFA) features of retinal capillary hemangioblastoma (RCH). This is an observational case series of three patients with von Hippel朙indau (VHL) disease and one patient with juxtapapillary RCH. All patients underwent FFA with a mydriatic fundus camera and OCTA with swept-source angio OCT. The FFA and OCTA characteristics of tumors were compared. In our series, FFA could identify tumors as small as the width of a third-order retinal artery, which was missed on clinical examination. OCTA identified these tiny tumors, but only those closer to the posterior pole. Both FFA and OCTA could identify the intrinsic vasculature and feeder vessel in juxtapapillary RCH. On OCTA, the tumors were better defined than in FFA. The depth of the lesion can be identified on OCTA. Feeder and the draining vessels could be identified precisely in OCTA than FFA, particularly in small tumors. OCTA can identify tumors in VHL missed on clinical examination. It can identify the feeder vessel and intrinsic vasculature of sessile juxtapapillary RCH and aids in its diagnosis. Tumors are better defined in OCTA than FFA due to the absence of leakage. However, FFA can identify nearly all the early tumors, but OCTA fails to image the peripheral tumors due to its smaller field and prolonged acquisition time. Technological advances and the development of wide-field OCTA in the future can be helpful in identifying all the unsuspected tumors in VHL disease.Item Congenital intrauterine infection like syndrome of microcephaly, intracranial calcification and CNS disease.(2002-09-09) Mishra, D; Gupta, V K; Nandan, D; Behal, DItem Correlation of Maternal Age with Prevalence of Chromosomal Anomalies in Patients of Anorectal Malformation(Society for Health Care & Research Development, 2019) Mishra, D; Verma, R. K; Rani, A; Sehgal, G; Pandey, A.Introduction: Aims: To identify the Anorectal malformations patients in North Indian region and then study the karyotype of these patients to evaluate cytogenetic aberrations and then correlate it with the maternal age. Subjects and Methods: Forty eight patients of anorectal malformation were selected from Department of Paediatric Surgery, KGMU, UP, Lucknow. Blood samples were collected and their cytogenetic study was done in the Department of Anatomy, KGMU-U.P, Lucknow. Karyotypes obtained were further analysed. Results: Out of 48 children enrolled in the study, karyogram could be obtained for 45 cases (93.75%). Maternal age at the time of birth of the child was <30 years in 91.1% cases. There were only 8.9% women who were >30 years of age at the time of birth of the child. However, proportion of those with anomalies was significantly higher in >30 years age group (75%) as compared to that in <30 years age group (2.4%). Conclusion: Although low maternal age was found most commonly, but number of cases with chromosomal anomalies was reported more in >30 years of age, which could be due to increased risk of congenital anomalies and malformations with advanced age.Item Epidermolytic hyperkeratosis with rickets.(2006-03-19) Nayak, Surajit; Behera, Samira Kumar; Acharjya, Basanti; Sahu, A; Mishra, DA 6-year-old child presented with generalized hyperkeratosis, most marked over the flexures; windswept deformity of the legs; and limping since 3 years. On the basis of the clinical, histopathologic and biochemical findings, he was diagnosed as a case of epidermolytic hyperkeratosis with rickets. He was treated with parenteral vitamin D3 and calcium supplements orally. Nutritional rickets has been reported in children with various types of ichthyosis like lamellar and X-linked types. We report this case of epidermolytic hyperkeratosis with rickets for its rarity.Item External dacryocystorhinostomy conventional surgery versus Pawar implant: A comparative study(All India Ophthalmological Society, 2019-07) Mishra, D; Bhushan, P; Sinha, BP; Bhaskar, G; Rao, RPurpose: External dacryocystorhinostomy (DCR) surgeries are cost-effective with excellent success rates. The present study was designed to compare the safety and efficacy of conventional external DCR versus external DCR using Pawar silicone implant in chronic dacryocystitis. Methods: This is a prospective, comparative, interventional case series over a period of 18 months with patients managed by external DCR surgery with and without Pawar implant. Institutional review board approval was obtained before the study. The success of the surgery was objectively measured by sac patency on syringing at the last follow up. Results: A total of 65 patients with chronic dacryocystitis were included in the study. The mean age of patients in the series was 41.43 years (median, 41 years; range, 12 years-60 years). All patients presented with epiphora (100%) and underwent external DCR and were chosen for conventional surgery (n = 33, 51%, group 1) or Pawar silicone implant surgery (n = 32, 49%, group 2) on a random basis. The mean duration of the surgery from the time of skin incision to skin closure for group 1 was 27.7 minutes (median, 26 minutes; range, 21-30 minutes) while in group 2, it was 75.5 minutes (median, 75 minutes; range, 60-88 minutes), which was statistically significant (P < 0.01). The success rate of the procedure done in group 1 was 90% which increased to 97% after the management of failed cases as compared to the success rate in group 2 of 91% and 94%, before and after the management of failed cases, respectively. Conclusion: External DCR using Pawar implant is a safe surgery which is faster than conventional external DCR with almost equal success rates between both the procedures.Item Follicular Eczema: A Commonly Misdiagnosed Dermatosis.(2012-07) Sardana, Kabir; Agarwal, P; Mishra, DItem Health professionals' characteristics associated with requisitioning electroencephalography in breath holding spells.(2007-09-07) Mishra, D; Archana,; Pensi, TriptiItem Helicobacter pylori in children.(1999-11-02) Mishra, D; Sibal, AHelicobacter pylori (Hp) infection is one of the most frequently encountered bacterial infections worldwide. Although strong epidemiological association exists between Hp infection and duodenal and gastric ulcers and gastric cancer in adults, the clinical spectrum of Hp infection in children is yet to be established. The increasing use of endoscopy as a diagnostic modality in gastroduodenal diseases in children has raised some questions regarding the role of Hp in causing symptoms in children and need for eradication therapy. Despite a variety of protocols, the standard therapy of Hp in children is still undecided. This article discusses the epidemiological and clinical spectrum of Hp infection in children and includes a review of various diagnostic modalities and treatment protocols for this infection.Item Hepatitis C in childhood.(2002-02-11) Sibal, A; Mishra, D; Arora, MThe prevalence of hepatitis C virus (HCV) infection is relatively low in childhood. Blood transfusion has been the principal route of acquisition in children but vertical transmission is gradually occupying primacy in the developed world. The risk of vertical transmission increases with higher maternal viraemia and human immuno-deficiency virus (HIV) co-infection but current international guidelines do not suggest avoidance of vaginal delivery and breastfeeding to minimise the risk of vertical transmission. The diagnosis of perinatal transmission is different from that in older child or adult and detection of HCV-RNA is essential. Although the natural history of HCV infection in children is not well characterised, almost 50-80% will progress to chronic hepatitis among vertically infected and blood transfusion acquired hepatitis C cases. Children have a lower viral load, lower ALT values and milder histological derangement as compared to adults with chronic hepatitis C cases. Experience of treatment of chronic hepatitis C in children is limited and still evolving. Few patients achieve spontaneous remission and progression to a more severe liver disease might occur in adult life. Here, the natural history, diagnosis and management of HCV infection in children are discussed with special emphasis on features which are different from adults.Item Hereditary coagulation factor X deficiency.(2005-12-21) Kumar, A; Mishra, K L; Kumar, A; Mishra, DStuart Prower factor (Factor X) deficiency is a rare hereditary autosomal recessive coagulation disorder. We have come across three cases in the course of last 20 years at our institute. These patients presented with prolonged bleeding after minor trauma, epistaxis, subcutaneous bluish black nodules and two of them presented with history of consanguinity in parents. Hematological findings in correlation with clinical manifestations revealed severe factor X deficiency.Item Hib, measles and varicella vaccine.(2000-11-22) Mishra, DItem Interaction between warfarin and tamoxifen: a case report.(2007-01-08) Mishra, D; Paudel, R; Kishore, P V; Palaian, S; Bista, D; Misra, PWarfarin is a commonly used anticoagulant with documented reports of drug interactions. Tamoxifen is used in the adjuvant hormonal treatment of women with oestrogen-receptor- positive breast cancer. Warfarin and tamoxifen are known to interact with each other with a resultant increase in the bleeding tendency. These reports are mainly from the white population. We report a case of drug interaction between warfarin and tamoxifen with an acute onset. This report suggests that when these drugs are co administered, careful monitoring of the coagulation profile is needed.Item Kawasaki disease--atypical presentation.(2001-03-08) Mishra, D; Uttam, R; Khilnani, PKawasaki disease, an acute systemic vasculitis of unknown etiology, is the leading cause of acquired heart disease in children in many parts of the world. It predominantly affects children under 5 years of age and is diagnosed clinically by the presence of characteristic clinical signs. Atypical patients, often younger than 1 year of age, manifest few early signs, usually have an incorrect admitting diagnosis and suffer from high morbidity and mortality. We report the presentation, clinical course and follow-up of a 3-month-old infant with atypical Kawasaki disease.Item Kuppuswamy's socioeconomic status scale--a revision.(2003-03-06) Mishra, D; Singh, H PItem Liver transplantation for fulminant hepatitis A infection.(2002-02-28) Mishra, D; Singh, R; Sibal, AItem Oxygen gas cylinder explosion.(1995-03-01) Mishra, DItem Perinatal infections.(2000-03-06) Mishra, D