Browsing by Author "Jahan, N"
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Item Assessment of Colour Blindness and Erythrocyte G6PD Enzyme Status among the School Children of Dhaka City.(2009-12) Yasmin, A; Jahan, N; Akhter, RBackground: Visual impairment due to colour blindness is an unusual suffering of the school children. It may be associated with erythrocyte G6PD enzyme deficiency. Objective: To find out defective vision due to colour blindness in apparently healthy school children and to measure erythrocyte G6PD enzyme level among them. Methods: This cross sectional study was carried out in the Department of Physiology, SSMC from 1st July 2007 to 31st June 2008. Five hundred (500) apparently healthy school children of old Dhaka, age ranged from 6 to 12 years irrespective of gender and race was selected as study population. Colour vision test was done by Ishihara’s test. Erythrocyte G6PD enzyme was measured among the colour blind children. All the results were compared to that of children with normal colour vision. Results: Five male children were detected to have partial red-green type of colour blindness. The percentage of colour blindness was statistically not significant (p>0.05) when compared to that of children with normal colour vision. Mean erythrocyte G6PD enzyme level of colour blind children was significantly lower (p<0.05) compared to that of children with normal colour vision. Presence of G6PD enzyme deficiency among the colour blind children did not show any clinical abnormalities might be due to different non symptomatic G6PD variants. Conclusion: Visual defect due to colour which blindness particularly red-green type might be present in apparently healthy school children associated with erythrocyte G6PD enzyme deficiency.Item A comparative study of body iron status and lipid profile in acute myocardial infarction patients.(2002-07-25) Sultana, N; Haque, M M; Ali, M S; Begum, B A; Jahan, N; Akter, S; Roy, MThis study was carried out to evaluate the relationship between body iron status and lipid profile in hospital admitted clinically diagnosed AMI patients considering the concept that there is a potential association between body iron status and coronary heart disease (CHD). Total 80 subjects were selected, of which 40 were healthy adults and 40 were AMI patients. Fasting blood samples were collected from healthy adults. Blood samples of AMI patients were collected within 24 hours of the attack of myocardial infarction. Body iron status was measured in term of 3 variables serum total iron concentration, TIBC and transferrin saturation. Lipid profile variables measure were total cholesterol, triglyceride, LDL-cholesterol and HDL-cholesterol. No correlation was found between serum iron and the variables of lipid profile. TIBC was found to maintain negative correlation with total cholesterol, triglyceride and LDL-cholesterol but positive correlation with HDL-cholesterol. Transferrin saturation was found to maintain strongly positive correlation with total cholesterol, triglyceride and LDL-cholesterol but strongly negative correlation with HDL-cholesterol. This correlation of TIBC and transferrin saturation with lipid profile supports the hypothesis that there is a potential association between body iron status and coronary heart disease.Item Effect of graded head-up tilt on parasympathetic reactivity.(1996-10-01) Jahan, N; Deepak, K K; Kaushal, N; Paudel, B HThirteen healthy subjects were tested for parasympathetic reactivity during head-up tilt and reversal of the tilt. Head-up tilt (70 degrees) resulted in significant increase in baseline heart rate and diastolic blood pressure. Head-up tilt also led to increased parasympathetic reactivity as measured by Valsalva manoeuvre and hand grip test. Heart rate response to deep breathing test did not change. The reversal of the tilt led to returning of heart responses to original values. Responses indicate towards enhanced parasympathetic reactivity during head-up tilt position.Item Prolonged stability of R plasmids KR61 and KR61-A in Salmonella host.(1995-04-01) Khatoon, H; Jahan, NThe R plasmids, KR61 and KR61-A, that were originally isolated from a clinical strain of Aerobacter aerogenes in 1971 and determined resistance to kanamycin (Km), neomycin (Nm), streptomycin (Sm), tetracycline (Tc); and ampicillin (Ap) respectively were found stable in Salmonella typhimurium LT2 even after 22 years of cultivation on antibiotic free media. KR61, carrying resistance to KmNmSmTc, not only maintained all its resistances but also maintained its conjugal transferability (RTF) as indicated by its subsequent transfer to Escherichia and Salmonella hosts. KR61-A that carried resistance to Ap and lacked an RTF could be mobilized by KR61 from S. typhimurium LT2, constructed to bear KR61-A and KR61, to E. coli recipients. S. typhimurium LT2 carrying KR61-A + KR61 (ApKmNmSmTc), showed the characteristic conjugal transfer of resistances in following three patterns: (i) Ap, (ii) KmNmSmTc and (iii) ApKmNmSmTc. The findings reported here are based on conjugal isolation of plasmids. Physical isolation of KR61 and KR61-A was never made.