Browsing by Author "Das, S K"
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Item Abridged life tables for rural West Bengal, 1969.(1975-01-01) Mukherjee, S P; Das, S KItem Abridged stay table for pulmonary tuberculosis patients in three selected hospitals of West Bengal.(1978-04-01) Das, S K; Sen, A KItem Absence of HTLV-I infection in some Indian populations.(1994-10-01) Roy, M; Das, M K; Ishida, T; Das, S K; Dey, B; Banerjee, S; Majumder, P PA total of 946 adults belonging to ten population groups of Uttar Pradesh and West Bengal were screened for HTLV-I using a gelatin particle agglutination test. The percentage of seroreactive cases varied from 0 to 5.8 per cent. The overall prevalence of seroreactivity was 2 per cent. Of the 19 seroreactive cases, 15 were subjected to Western blot analysis, none could be confirmed. HTLV-I infection is, therefore, absent in these populations.Item Acute intermittent porphyria in Bikaner.(1991-03-01) Das, S KItem Acute intracerebral haematoma--an unusual presentation of herpes simplex encephalitis.(2004-01-07) Biswas, A; Das, S K; Roy, T; Dhibar, T; Ghorai, S PA young man presented with acute headache, behavioral abnormality and CT scan evidence of intracerebral hematoma. Detailed investigation established its infective origin due to herpes simplex virus type-I. The patient made an excellent recovery following a course of acyclovir. Frank intracerebral haematoma in the form of well defined mass on CT scan in patient with herpes simplex encephalitis is extremely rare.Item Adult moyamoya disease.(1996-09-01) Saha, S P; Ganguli, P K; Das, S K; Maiti, BItem Antibodies to Entamoeba histolytica in patients with rheumatoid arthritis.(1985-07-01) Singh, I P; Das, S K; Sharma, P; Dutta, G P; Agarwal, S SItem Arthropathic presentation of Wilson's disease.(2004-03-08) Misra, A K; Biswas, A; Ganguly, G; Ghosh, A; Das, S K; Roy, TA patient is described who presented with polyarthritis involving small and large joints of limbs with later onset of tremors affecting all four extremities. Investigations including genetic study confirmed the diagnosis of Wilson's disease (WD). The case highlights the importance of considering the possibility of WD in young patient presenting with repetitive unexplained joint symptoms with or without tremor.Item Bilateral basal ganglia haemorrhage--uncommon manifestation of methanol poisoning.(1996-11-01) Ganguly, G; Banerjee, A; Mukherjee, S; Das, S K; Maity, BItem Bilateral intracerebral haemorrhages: an atypical presentation of Japanese encephalitis.(2005-02-26) Sarkar, N; Roy, B K; Das, S K; Roy, T; Dhibar, T; Ghorai, ShyamapadaJapanese encephalitis is common human endemic encephalitis seen over various parts of the world. Usual presenting features include an encephalitic syndrome, symptoms of frontal lobe, basal ganglia and thalamic involvement. Characteristic radiological picture is bilateral thalamic and basal ganglia hypo density in the CT scan and hypo-intensity in T1 and hyperintensity in T2 weighted image in MRI. Very rarely occurrence of bilateral hemorrhage may be seen in these regions. This radiological change may be early indicator of the disease before serological confirmation by the available diagnostic modalities. In this communication, we have reported a case of Japanese encephalitis presented with bilateral basal ganglia hemorrhages.Item Biochemical toxicity study on rat brain upon co-exposure to aluminium and ethanol.(2005-06) Nayak, P; Das, S K; Vasudevan, D MAluminium and alcohol are well known neuro toxins. Co-exposure of these neuro toxins has been studied in rats. Alcohol exposure significantly affected the aluminium content, protein content, acid phosphatase activity, alkaline phosphatase activity, alanine aminotransferase activity, glutathione-S-transferase activity, and glucose 6-phosphate dehy-drogenase activity of brain. Aluminium exposure, on the other hand, contributed significantly only in the alterations of aluminium content, acid phosphatase activity, and aspartate aminotransf erase activity of brain of rats in the present study. The interaction of both aluminium intoxication and alcohol exposure is significant only in the case of acid phosphatase and glutathione-S-transferase activities of brain. Therefore, from the observations of the present investigation, it can be suggested that the general neurotoxic-ity produced by aluminium is not modified by alcohol. However, the aluminium load and oxidative stress, caused by aluminium exposure, may be influenced by alcohol co-exposure.Item Blastic transformation in chronic granulocytic leukaemia.(1984-05-01) Singh, V P; Dube, B; Dube, R K; Srivastava, A K; Sahu, B B; Bajpai, H S; Das, S KItem Botulinum toxin in migraine.(2003-09-09) Mishra, A; Ghosh, B; Das, S KItem A case of neurosarcoidosis presenting with multiple cranial nerve palsy.(2003-03-04) Bandyopadhyay, T; Das, D; Das, S K; Ghosh, AItem Cerebrotendinous xanthomatosis.(2002-09-09) Sen, A; Ghosh, B; Kundu, T N; Das, S K; Sengupta, S RItem Characterization of primed lymphocytes on the basic of sensitivity of chromatin to DNase I.(1997-11-06) Das, S K; Chakravarty, A KCertain qualitative criteria for primed lymphocytes in the expression of cytotoxic function have been studied. Unlike normal lymphocytes, primed lymphocytes expressed cytotoxicity even when DNA synthesis and new gene expression were inhibited by hydroxyurea (HU) and bromodeoxyuridine (BU) respectively. Such differential cytotoxic expression in presence of HU and BU by primed lymphocytes might have their basis in conformational change within the chromatin. Chromatin from primed lymphocytes was more susceptible to DNase I digestion than virgin lymphocytes indicating exposition of more DNase I sensitive sites in primed state. The result suggest the presence of more ready to act sites for the polymerases in the genomic material of primed lymphocytes even at quiescent state.Item Climbing efficiency with different modes of load carriage.(1966-09-01) Das, S K; Saha, HItem Clinical profile of multiple sclerosis in Bengal.(1999-03-26) Gangopadhyay, G; Das, S K; Sarda, P; Saha, S P; Gangopadhyay, P K; Roy, T N; Maity, BForty five patients of multiple sclerosis diagnosed on the basis of Poser's criteria from West Bengal were studied. The male-female ratio was 1:1.5, mean age of onset 31.83 years in male and 29.11 years in females. The maximum cases were between the 3rd and 4th decade.Definite MS comprised of 60%, while remaining 40% were probable.Visual impairment (53.33%), weakness of limbs (31.11%) and sensory paraesthesia (20%) were the common presenting symptoms whereas pyramidal tract involvement (93.33%) with absent abdominal reflexes (90%) and optic pallor (64.44%) were common signs. Posterior column and spinothalamic sensations were involved in 55% and 51% of cases respectively. Inter-nuclear ophthalmoplegia was present in 6.66% of cases. Pattern of involvement commonly showed three or more sites of lesion. Optico-spinal affection was present in 22.2% of cases. Relapsing and remitting course was found in 48. 91%, relapsing and progressive course in 33.33% and chronic progressive in 17.8%. MRI of brain showed positive results in 16 out of 23 cases. CSF study showed increased positivity in estimation of immunoglobulin level than oligoclonal band. Findings revalidate the disease pattern as being similar to that in other parts of India as well as Asia.Item Clinical profile of myasthenia gravis.(1998-11-07) Saha, S P; Mukherjee, S; Das, S K; Ganguly, P K; Roy, T N; Maiti, B; Bhattacharya, S; Sarkar, SSeventy three patients with myasthenia gravis were studied over 9 years period (1987-1995) in departments of neuromedicine, respiratory care unit, cardiothoracic unit of Institute of Postgraduate Medical Education and Research and Bangur Institute of Neurology, Calcutta, with reference to their clinical presentations, laboratory findings and various modes of treatment. Commonest age of presentation was 5th decade in men and 3rd decade in women. Fifty five percent of patients belong to type 2A myasthenia gravis (Osserman classification). Presentation was insidious (67.2%) and course was slowly progressive (65.7%) in majority of cases. Fatigability and ptosis were commonest clinical presentation and diurnal variation was noticed in 60% of cases. Edrophonium test was positive in 90.4% of cases and repetitive nerve stimulation showed 93.5% positivity in 30 cases. 27 patients (36.9%) underwent thymectomy and out of these, 89% of patients showed hyperplastic change and thymoma in 11% of cases. Mortality rate including both operated and nonoperated patients was recorded to be 9.6%. We observed earlier onset of myasthenia in male, higher incidence of oculo-bulbar involvement and lower incidence of respiratory problem and thymoma.Item Clinical trial of ethyl acetate extract of gum gugulu (gugulipid) in primary hyperlipidemia.(1986-04-01) Gopal, K; Saran, R K; Nityanand, S; Gupta, P P; Hasan, M; Das, S K; Sinha, N; Agarwal, S S