About IMSEAR

Index Medicus for South-East Asia Region (IMSEAR) is an archive of selected publications in health sciences in the WHO South-East Asia Region. Materials in IMSEAR include formally published health science journals, health reports and documents.

Items in IMSEAR are organized under categories, sub-categories and collections reflecting type of materials, countries and journal titles. In addition to metadata of each item, original full text documents or links to original documents are provided whenever available, under Open Archives Initiative (OAI) framework. Items in IMSEAR can also be harvested through OAI-PMH at the base URL: https://imsear.searo.who.int/server/oai/request.

You are welcome to register yourself at the IMSEAR and subscribe to our collections to receive email alerts whenever new items are added to the collection. If you would like to include your publications in IMSEAR, please contact searolibrary@who.int at the WHO Regional Office for South-East Asia.

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IMSEAR Working Group
WHO South-East Asia Region

 

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Clinical and Epidemiological Study of Melasma in Men Attending Tertiary Referral Hospital in South India
(International Research Organization for Life & Health Sciences, 2024-01) Charles, BGS; Lakshminarayan, D; Shaik, A; Praveen, SV
Background: Melasma is one of the most common causes of acquired facial hypermelanosis that affects both genders and all races. Unlike melasma in women, which has been studied in detail, there is a paucity of studies on the clinico-epidemiological pattern of melasma in men. Aim: To study the clinical profile and epidemiology of melasma in males. Materials and Methods: This is a single-center observational study in which 108 male patients with melasma, belonging to the age group 20–60 years, were selected. A detailed clinical history was taken with the help of a well-structured proforma, which specifically included history of occupation, number of hours of sun exposure, family history, use of any topical or systemic medications, and history of any chronic illness. Following which, a wood lamp examination was done. Results: The most affected age ranges were 31–35 years (n = 38, 35.18%), followed by 36–40 years (n = 27, 25%). The prevalence of melasma among males in this study was found to be 7.15%. In this study, 48.1% had Fitzpatrick skin type IV, 31.48% had Fitzpatrick skin type III, 12.03% had Fitzpatrick skin type V, and 6.48% had Fitzpatrick skin type VI. 33.3% expressed a positive family history. Occupational sun exposure was seen in 80.55% of the cases, whereas 19.44% of patients reported exposure to heat at work place for a significant portion of the day. In this study, the majority of the patients (n = 32, 29.6%) had no history of topical application prior to the onset of the disease. 22 patients (20.37%) had associated type 2 diabetes mellitus, 8 patients (7.4%) had associated thyroid disorder (hypothyroidism), and 4 cases (3.7%) had associated chronic kidney disease. Epidermal melasma was found in the majority of cases (51.85%) on Wood’s Lamp examination; 22 cases (20.37%) had a mixed type of melasma, and 12 cases (11.1%) had a dermal type of melasma. Among the cases, 51 (47.2%) had a melasma area and severity index score between 5 and 10. Conclusion: Though the prevalence of melasma is more in India, very few men are diagnosed with it. This could be due to comparatively less cosmetic concern among males in this part of the state and a fewer number of patients attending the outpatient department. The principal risk factors for melasma are sun exposure and family history. Epidermal melasma was found in the majority of cases.
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Prevalence and Determinants of Undernutrition among Children Aged 6–59 Months in Northeast India: A Hospital-based Cross-sectional Study
(International Research Organization for Life & Health Sciences, 2024-01) Devi, RR; Singh, CI; Omita, T; Gitaranjan, T
Background and Objectives: Undernutrition (UN) is one of the leading causes of morbidity and mortality in children under 5 years of age in developing countries. The prevalence of UN is high and its causes are multifactorial. To estimate the prevalence of UN and identify its determinants among children aged 6–59 months attending pediatric outpatient department at a tertiary care institute. Methods: A cross-sectional study was conducted from June 2020 to May 2021 on 360 children. All children were examined clinically, including anthropometric measurements. Multiple logistic regression analysis was carried out to identify the determinants of different categories of UN. Results: The mean age of presentation was 25.3 months ± 14.86 standard deviations, with males comprising 52.3%. The prevalence of stunting was highest (26.39%), followed by underweight (25.28%) and wasting (15.83%). The important determinants of being underweight were exclusively breastfeeding <6 months, nuclear family, and incomplete immunization. Younger age, unprotected water, and comorbidities with anemia, diarrhea, and acute respiratory tract infection were the main predictors for stunting. The major determinants for wasting were lower mother’s education and improper hand hygiene in addition to nuclear family and incomplete immunization. Conclusion: Identifying determinants of the UN will help in addressing the policymakers to improve maternal literacy, promote breastfeeding and nutrition programs, provide infection control, and better sanitation and water facilities at the community level. Strengthening the screening for the nutritional status of children under 5 years should be performed in every childcare/facility base center.
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Impact of COVID-19 Pandemic on Stress Level and its Association with Gingival and Periodontal Status of Nursing Staffs of an Institution: A Cross-sectional Study
(International Research Organization for Life & Health Sciences, 2024-01) Kumari, P; Shruthi, S; Nisha, KJ; Rukmini, N
Introduction: Coronavirus disease (COVID-19) has created an unprecedented situation worldwide and has set forth an array of challenges before us. Health-care workers especially nursing staffs have encountered a considerable degree of stress during the pandemic. A strong association exists between stress level and periodontal disease, hence creating a link between deterioration of periodontal status by COVID-19 pandemic-induced stress. Aims and Objectives: The aim of the study is to estimate the impact of COVID-19 pandemic on stress levels and its correlation with gingival and periodontal status in nursing staff of an institution in Bangalore. Materials and Methods: This is a cross-sectional questionnaire survey on 265 nursing staffs of the institution during the period of March and April 2022. Data for stress were obtained from social impact of COVID-19 and self-formulated questionnaire survey with demographic details. Diagnosis of gingival and periodontal status was given according to 2017 classification of periodontal and peri-implant disease and conditions by the American Academy of Periodontology and the European Federation of Periodontology. Results: COVID-19 had a negative impact on stress level of nursing staffs. All age groups were found to be under moderateto-severe stress. Conclusion: A relatively high proportion of nursing staff experienced moderate-to-severe stress during the third wave of COVID-19 pandemic and a positive association was seen to exist between stress and periodontitis.
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Pleomorphic Adenoma: A Case Series Study
(International Research Organization for Life & Health Sciences, 2024-07) Kumar, A; Anjum, R; Kaur, M; Khajuria, N; Ettishree; Sepolia, N.
Pleomorphic adenoma (PA) is the most common of benign salivary gland tumors (80%). It is an epithelial derivation and normally appears as a well circumscribed, benign tumor, which may or may not be encapsulated. PA affects both the major and minor salivary glands and accounts for 40–70% of all tumors. The parotid gland is the most affected major salivary gland. Globally, 13.9–51.4% of all salivary gland tumors arise from an intraoral site, and 34.7–67.1% of them are benign. Usually manifest as a slow progressing asymptomatic swelling. The diagnosis is made by the clinical and histopathological examination. The treatment of PA is surgical excision. Malignant transformation, though rare, has been reported. In this article, we report cases series study of PA with a brief literature review.The average age of the patients (five females) was 33.8 years. The average site of involvement includes a parotid gland 0.4%, a minor salivary gland, and a submandibular gland 0.2%. All the cases were predominantly seen in females.
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Comparative Analysis and Evaluation of Functional Outcome of Extended Curettage, Cauterization of Margins with Appropriate Fixation, and Bone Cementing with or without Incorporation of Zoledronic Acid Powder in Grade III Campanacci Giant Cell Tumor Around Knee Joint
(International Research Organization for Life & Health Sciences, 2024-07) Sahu, MK; Jain, VK; Srivastava, P; Jain, SN; Baghel, P; Parihar, GS
Introduction: Treatment of giant cell tumors (GCT) Campanacci grade III remains challenging till date because of the high recurrence rate of the disease and notorious post-operative complications which lead to significant morbidity in patients. Among the various types of surgical procedures, we chose extended curettage, cauterization of margins followed by appropriate fixation, and bone cementing with and without incorporation of zoledronic acid. This study was conducted to evaluate the functional outcome of the aforementioned procedure. Materials and Methods: A prospective analytical study of 10 patients of grade III Campanacci GCT was included in the study and all patients were planned for surgical intervention and included in this study. The patients were randomly divided into two groups, of which one group was taken for extended curettage, cauterization of margins followed by appropriate fixation with bone cementing alone, and in the other group same procedure was done with the incorporation of zoledronic acid in bone cement. Lysholm scoring was used to evaluate the outcome in follow-up. Results: The mean Lysholm score in the pre-operative period was 0.5, whereas the mean Lysholm score at 6 weeks was 21.5, 74.7 at 12 weeks, and 87.5 at 24 weeks post-operative period. Upon comparison between the mean Lysholm score at 6, 12, and 24 weeks post-operative period in the zoledronic acid application group and zoledronic acid non-application group, it was 21.80 versus 21.20 (P = 0.412), 75 versus 74.40 (P = 0.644), and 89 versus 86 (P = 0.111), respectively. Regarding postoperative complications among the study subjects, a total of 3 patients (30%) developed post-operative complications, among which 2 patients developed swelling (20%) and 1 patient (10%) developed joint pain. Conclusion: Although not statistically significant, there was a trend of better functional outcomes in terms of the Lysholm scoring system in cases of grade III Campanacci GCT around the knee joint treated with extended curettage, cauterization of margins with appropriate fixation, and bone cementing with or without incorporation of zoledronic acid powder